I put a gazillion happy miles on an Aluminum block Slant Six.
It also took really well to overheating.
Giving someone a ride to the airport in winter decades ago, I realized I had my town driving cardboard radiator air blocker was fully in place, and it overheated bad while climbing a long freeway hill I had no choice but to ride it out.
As usual with Mopar engines, no harm done at all.