In about 1967, Hot Rod magazine did a dyno project on a '67 383 4bbl. It was a then-new short block when they started. As things progressed to about 425 horsepower or so, nothing seemed to help, until they "clearanced" the pistons a bit.
The old Street Hemi 284/284 Purple Shaft cam, using the Mopar Perf Head Porting Templates, an updated Edelbrock dual-plane intake, 780cfm carb (of your choice), headers or possibly the factory HP exhaust manifolds, 2.5" exhaust system with lower-restriction mufflers, in front of an upgraded TorqueFlite 727, probably about a 2600rpm stall converter, and 3.55 SureGrip would probably be a good package? There probably are better cams now, as Lunati has some that seem to be pretty good. Just as there are probably better-port heads readily available, too. KEY thing is to match all of the components to work together rather than just an "assemblabe" of parts.
THEN, upgrade the brake system and ensure the suspension components are in very good condition, too! Which can also mean better tires.
In some of the Mopar Perf Catalogs, there used to be a list of things to change in order to get close to particualr 1/4 mile ETs. Something like that might be helpful, too, as would be reading (AND understanding) the B/RB Mopar Perf Race Manual.
Enjoy!
CBODY67