If your goal is a powerful C-body, a well-built 500-550hp bigblock stroker will be far cheaper, simpler, easier to build, etc.
If your goal is a modern EFI engine, a 5.7 would be much simpler than the 488, and 6.1 or 6.4 would offer more power in the same envelope.
If you're after bragging rights of an oddball drivetrain, be aware that many of those ambitious projects result in an unfinished car sold at a major loss.
The 488 is longer, so harder to fit, and you need to change to a Viper-compatible transmission also (it shares the bell pattern with the Cummins). Which means either fitting a 6-speed (major tunnel reconstruction plus conversion to 3-pedal), a 518OD (mild reconstruction) or finding a Cummins 727 (do they exist?) and tweaking it to perform nicely with a high-rev gas engine instead of a low-rpm diesel.
Plus all the ECU stuff, which will be harder to figure out than the G3 hemi stuff.